The wood from sycamore is coarse-grained and slightly twisted, but not very strong. It is used to make boxes, crates, yokes, furniture, butcher's blocks, and woodenware. Baskets may also be fashioned from the bark , or thin strips of wood.

Some trees are grown for timber that may be used for interior trim work, veneer, or pulpwood. This fast-growing, long-lived species is frequently planted as an ornamental in backyards or along roadsides. It is also suitable for planting along watercourses, where the interlacing roots minimize stream bank erosion.